Fri Apr 01 2022

119 articles - From Saturday Mar 26 2022 to Friday Apr 01 2022

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Guidelines

Guidelines, position statements, white papers, technical reviews, consensus statements, etc…

Am J Gastroenterol

Diagnosis and Management of Barrett's Esophagus: An Updated ACG Guideline.

We recommend endoscopic eradication therapy for patients with BE and high-grade dysplasia and those with BE and low-grade dysplasia. We propose structured surveillance intervals for patients with dysplastic BE after successful ablation based on the baseline degree of dysplasia. We could not make recommendations regarding chemoprevention or use of biomarkers in routine practice due to insufficient data.

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GUIDELINE TO PRACTICE: ACUTE ON CHRONIC LIVER FAILURE.

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Management of Patients on Anticoagulants and Antiplatelets During Acute Gastrointestinal Bleeding and the Peri-Endoscopic Period: A Clinical Practice Guideline Dissemination Tool.

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Gastroenterology

AGA Clinical Practice Update on the Role of Diet in Irritable Bowel Syndrome: Expert Review.

BEST PRACTICE ADVICE 7: The low-FODMAP diet consists of the following 3 phases: 1) restriction (lasting no more than 4-6 weeks), 2) reintroduction of FODMAP foods, and 3) personalization based on results from reintroduction. BEST PRACTICE ADVICE 8: Although observational studies found that most patients with IBS improve with a gluten-free diet, randomized controlled trials have yielded mixed results. BEST PRACTICE ADVICE 9: There are limited data showing that selected biomarkers can predict response to diet interventions in patients with IBS, but there is insufficient evidence to support their routine use in clinical practice.

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Rio de Janeiro Global Consensus on Landmarks, Definitions and Classifications in Barrett's Esophagus: World Endoscopy Organization Delphi Study.

We have developed evidence-based consensus-driven statements on endoscopic landmarks, definitions, and classifications of BE. These recommendations may facilitate global uniform reporting in BE.

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Gastrointest Endosc

Adherence to follow-up guidelines after high-risk colorectal polyp removal: a population-based study.

Adherence to follow-up guidelines was poor inappropriate intervals were more often longer than recommended. Patients with written follow-up instructions and who underwent their follow-up colonoscopy mostly followed these instructions. Ensuring adherence to guidelines and giving written instructions to patients should be primary goals to achieve effective follow-up. Gastroenterologists' training should be improved in this way.

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Hepatology

Consensus subtypes of hepatocellular carcinoma associated with clinical outcomes and genomic phenotypes.

Five HCC subtypes are correlated with genomic phenotypes and clinical outcomes and highly conserved in pre-clinical models, providing a framework for selecting the most appropriate models for preclinical studies.

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Meta-analysis

meta-analyses and systematic reviews

Aliment Pharmacol Ther

Effectiveness and safety of SARS-CoV-2 vaccine in Inflammatory Bowel Disease patients: A systematic review, meta-analysis and meta-regression.

In summary, the systematic review and meta-analysis suggest that SARS-CoV-2 vaccine is safe and effective in IBD patients.

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Systematic review and meta-analysis: incidence of variceal hemorrhage in patients with cirrhosis undergoing transesophageal echocardiography.

The risk of bleeding complications following TEE is low in patients with cirrhosis, suggesting TEE is safe and risk stratification with upper endoscopy may not be necessary.

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Neurogastroenterol Motil

Quantification of gastric emptying with magnetic resonance imaging in healthy volunteers: A systematic review.

As observed in this systematic review, MRI is a flexible tool for assessing GE. Different protocols were analyzed, showing an equal capacity to assess the GE. However, many items in these protocols still require further investigation to obtain a common standard and increase this assessment quality.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Aliment Pharmacol Ther

The effect of gluten in adolescents and young adults with gastrointestinal symptoms: A blinded randomised cross-over trial.

Compared with placebo, adding gluten to the diet did not induce gastrointestinal symptoms or worsened mental health in adolescents recruited from a population-based cohort. The trial registration

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Toward transmural healing: Sonographic healing is associated with improved long-term outcomes in patients with Crohn's disease.

In patients with CD in clinical remission, sonographic healing is associated with improved clinical outcomes. Further studies are needed to determine whether sonographic healing should be a treatment target.

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Am J Gastroenterol

Burden of Constipation: Looking Beyond Bowel Movements.

For those who seek help, only one-fifth feel that their constipation symptoms are well managed. Notable sex and cultural differences exist regarding individuals consulting their HCP about constipation. Many individuals with CIC and IBS-C remain inadequately managed and unduly affected, contributing to the high social and economic burden of these conditions.

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Celiac Disease and the Susceptibility of COVID-19 and the Risk of Severe COVID-19: A Mendelian Randomization Study.

Our results suggested that it may be unnecessary to take extra COVID-19 precaution in CeD patients.

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Effect of chronic comorbidities on follow-up colonoscopy after positive colorectal cancer screening results: a population-based cohort study.

Persons with medical and mental health conditions had lower colonoscopy rates after FOBT+ than those without these conditions. Better strategies are needed to optimize colorectal cancer screening and follow-up in individuals with comorbidities.

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Effective Communication Strategies and Tools for Improving Treatment Outcomes in Patients With Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation.

Currently, there are multiple symptom and quality-of-life scales available to assist healthcare providers in this endeavor. These scales also allow for the monitoring of constipation-related symptoms and symptom severity. When using patient self-assessments to measure treatment responses, scale selection may depend on the number of symptoms being assessed, the duration and frequency of assessments, and patients' comprehension and language skills.

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Individuals with eosinophilic esophagitis are at greater risk of later psychiatric disorder.

Individuals with EoE may be at greater risk of psychiatric disease than their siblings and the general population. This risk needs to be considered in clinical care to detect, prevent, and treat comorbidity.

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Large Hepatic Adenomas and Hepatic Adenomatosis: A multicenter study of risk factors, interventions, and complications.

In this large HCA cohort, obesity and metabolic comorbidities were important risk factors associated with large HCA and adenomatosis. Long term adverse outcomes were infrequent, 5% had tumor hemorrhage and one exhibited malignant transformation.

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Lung infection impacts access to treatment and short-term outcome in patients with severe alcohol-related hepatitis treated with corticosteroids.

Lung infection is frequent during severe AH and influences mortality at admission and after steroid initiation. These results emphasize the need for specific management of lung infection during the course of AH.

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Mechanisms of Action of Current Pharmacologic Options for the Treatment of Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation.

Some constipation treatments, such as stimulant laxatives, may increase bowel movement frequency but are ineffective at relieving, and may even exacerbate, abdominal symptoms. On the contrary, prescription treatments, such as the guanylyl cyclase-C agonists, for example, may improve bowel symptoms and reduce visceral hypersensitivity. This review summarizes the mechanisms of action of commonly used over-the-counter and prescription therapies for chronic idiopathic constipation and irritable bowel syndrome with constipation, outlining how these mechanisms contribute to the efficacy and safety of each treatment option.

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Percutaneous Tibial Nerve Stimulation vs Sham Stimulation for Fecal Incontinence in Women: NeurOmodulaTion for Accidental Bowel Leakage Randomized Clinical Trial.

Although symptom reduction after 12 weeks of PTNS met a threshold of clinical importance, it did not differ from sham stimulation. These data do not support the use of PTNS as conducted for the treatment of FI in women.

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Real-World Treatment Strategies to Improve Outcomes in Patients With Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation.

Should initial prescription treatments fail, retrying past treatment options (if not adequately trialed initially), combining agents from alternative classes, or use of adjunctive therapies may be considered. Given the broad spectrum of available agents, therapy should be tailored by mutual decision-making between the patient and practitioner. Overall, patients need to be actively monitored and managed to maximize clinical outcomes.

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Thyroid Nodules in Children with Familial Adenomatous Polyposis.

Thyroid ultrasound screening in adolescence may benefit females with FAP but has limited utility in males.

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Clin Gastroenterol Hepatol

An Office-Based, Point-Of-Care Test Predicts Treatment Outcomes with Community-Based Pelvic Floor Physical Therapy in Patients with Chronic Constipation.

RED offers an opportunity to disrupt the paradigm by offering a personalized approach to managing chronic constipation in the community.([NCT04159350]).

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Are they side effects? Extra-intestinal symptoms reported during clinical trials of IBS may be more severe at baseline.

Our study suggests that participants with IBS often experience extra-intestinal symptoms at baseline and that these symptoms generally improve in severity over the course of a clinical trial, regardless of the treatment arm. Systematic assessment of extra-intestinal symptoms at the beginning of a clinical trial is necessary to determine more definitively whether these symptoms may be considered an adverse event attributable to a study medication.

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Comparison of quality measures for detection of neoplasia at screening colonoscopy.

This large observational study confirmed the inverse association between ADR and CRC risk and death. The PDR and APC quality measures appear to be comparable to ADR.

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Low Daily Step Count is Associated with a High Risk of Hospital Admission and Death in Community-Dwelling Patients with Cirrhosis.

Daily step count predicted hospital admission and mortality rates in patients with cirrhosis, similar to the current standard frailty metrics. Incorporation of a physical training-dedicated smartphone application was associated with increased PAT usage and steps reporting.

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Patients with acute-on-chronic liver failure have greater healthcare resource utilization after liver transplantation.

Patients with ACLF at LT, particularly ACLF-3, have greater post-transplant healthcare resource utilization.

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Polygenic risk score for defining personalized surveillance intervals after adenoma detection and removal at colonoscopy.

Consideration of genetic predisposition to CRC risk, as determined by a PRS, could help to define personalized, risk-adapted surveillance intervals after detection and removal of adenomas at screening colonoscopy. However, whether the risk variation is strong enough to direct clinical risk stratification needs to be further explored.

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redicting the onset of hepatitis B virus-related acute-on-chronic liver failure.

A new prognostic score based on 4 predictors can accurately predict the 7/14/28-day onset of ACLF in patients with acute deterioration of HBV-related chronic liver disease and might be used to guide clinical management.

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The natural history of advanced chronic liver disease defined by transient elastography.

Liver stiffness, ALBI score, and disease aetiology are each associated with outcomes in a large contemporary cohort with ACLD. EHR data can be used to define clinical progression in these patients, facilitating large clinical effectiveness trials and cost-effectiveness analyses.

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Endoscopy

Artificial Intelligence-Assisted Staging of Barrett's Carcinoma.

Clinically important decision-making on endoscopic therapy can be achieved with a high degree of certainty using artificial intelligence.

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Rate of pancreatic cancer following a negative endoscopic ultrasound and associated factors.

PEPC was associated with a higher cumulative mortality at 1 year (hazard ratio 1.12, 95%CI 1.02-1.24), with only 14% of PEPC patients (95%CI 12%-17%) having a surgical resection, compared with 21% (95%CI 20%-22%) of controls. CONCLUSIONS : PEPC occurred in 6.5% of patients and was associated with chronic pancreatitis, older age, more co-morbidities, and specifically diabetes mellitus. PEPC was associated with a worse prognosis and lower surgical resection rates.

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Gastroenterology

Relative Contribution of Disease Activity and Psychological Health to Prognosis of Inflammatory Bowel Disease During 6.5 years of Longitudinal Follow-up.

Psychological factors are important determinants of poor prognostic outcomes in IBD and should be considered as a therapeutic target.

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Gastrointest Endosc

Assessment of post-manual cleaning adenosine triphosphate tests to prevent the use of contaminated duodenoscopes and linear echoendoscopes: the DETECT study.

Post-manual cleaning ATP tests do not reduce post-HLD gut flora contamination rates of DLE. Hence, post-cleaning ATP tests are not suited as a means for quality control of endoscope reprocessing.

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Hepatology

ATP7B gene therapy of autologous reprogrammed hepatocytes alleviates copper accumulation in a murine model of Wilson's disease.

We established a novel system of autologous reprogrammed WD hepatocytes and achieved ATP7B gene therapy in vitro. LPC-ATP7B-Heps transplantation demonstrated therapeutic efficacy on copper homeostasis in a murine model of WD.

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Bile multi-omics analysis classifies lipid species and microbial peptides predictive of Carcinoma of Gall bladder.

Bile sample of CAGB patients show significant reduction in lipid species and increase in bacterial taxa. Our study identifies a core set of bile lipidome and meta-proteome signature which may offer universal utility for early diagnosis of gall-bladder carcinoma.

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Cellular heterogeneity and transcriptomic profiles during intrahepatic cholangiocarcinoma initiation and progression.

Stress-responding and ICC proliferating subtypes were identified, and Zmiz1 and Ybx1 were revealed as core transcription factors in these subtypes. Fibroblast-endothelial cell interaction promotes ICC development.

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IL-1 receptor antagonist plus pentoxifylline and zinc for severe alcohol-associated hepatitis.

A combination of anakinra, pentoxifylline plus zinc provides similar survival benefits compared to corticosteroid therapy in severe AH.

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Malignant progression of liver cancer progenitors requires KAT7-acetylated and cytoplasm-translocated G-protein GaS.

Malignant progression of HcPCs requires increased K28-acetylated and cytoplasm-translocated GaS, causing enhanced response to IL-6 and driving premalignant HcPCs to fully established HCC, which provides mechanistic insight and potential target for preventing hepatocarcinogenesis.

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PNPLA3 rs738409 and Risk of Fibrosis in NAFLD: Exploring Mediation Pathways Through Intermediate Histological Features.

In NAFLD, nearly half of the total effect of the rs738409 G allele on fibrosis severity could be explained by a direct pathway, suggesting that rs738409 may promote fibrosis development by activating specific fibrogenic pathways. A large proportion of the indirect effect of rs738409 on fibrosis severity is mediated through portal inflammation.

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Reliability of extracellular contrast vs. gadoxetic acid in assessing small liver lesions using LI-RADS v.2018 and EASL criteria.

Agreement for definite hepatocellular carcinoma was substantial and similar for both scoring systems and the two contrast agents in small focal liver lesions. The agreement for LI-RADS categorization was lower for both contrast agents, and including LI-RADS ancillary features did not improve the agreement.

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Reliability of Histologic Assessment for NAFLD and Development of an Expanded NAFLD Activity Score.

After extensive preparation among a group of experienced pathologists, we demonstrated improved reliability of multiple existing histologic NAFLD indices and fibrosis staging systems. Hepatocyte ballooning and MDBs most strongly correlated with disease activity and were used for the new expanded NAS. Further validation including evaluation of responsiveness is required.

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Risk of liver-related events by age and diabetes duration in diabetic patients with non-alcoholic fatty liver disease.

Age rather than duration of T2D predicts liver-related events in NAFLD patients with T2D. It is reasonable to screen NAFLD patients with T2D for advanced liver disease starting at 50 years of age.

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Variability in Serum Creatinine is Associated with Waitlist and Post-Liver Transplant Mortality in Cirrhosis Patients.

This study informs the long-term impact of the variation in kidney function we al see in clinic practice. These data highlight that al fluctuations in sCr are associated with worse pre-and post-liver transplant outcomes.

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Inflamm Bowel Dis

Vedolizumab Antagonizes MAdCAM-1-Dependent Human Placental Cytotrophoblast Adhesion and Invasion In Vitro.

This study revealed a previously unrecognized role for a4ß7 and MAdCAM-1 in human placentation. More clinical and histological data from Vedolizumab-treated pregnant patients will be necessary to determine whether this medication poses any risk to the mother and fetus.

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J Crohns Colitis

Cellular and humoral immune responses to SARS-CoV-2 vaccination in inflammatory bowel disease patients.

In vaccinees with low or borderline IGRA, treatment with TNF-alpha inhibitors was the most frequent. In individuals with a significant drop in anti-spike antibody levels, plasmatic interferon-gamma concentrations after the specific SARS-CoV-2 stimulation were also insufficient. Simple humoral and cellular post-vaccination monitoring is advisable in IBD patients so that repeated vaccine doses may be scheduled.

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IL10 secretion endows intestinal human iNKT cells with regulatory functions towards pathogenic T lymphocytes.

Moreover, an intestinal microbial community enriched in SCFA-producing bacteria sustained the production of IL10 by iNKT cells. Finally, IL10- deficient iNKT cell failed to control the pathogenic activity of adoptively transferred CD4+ T cells in an experimental colitis model. These results describe an unprecedent IL10-mediated immunoregulatory role of intestinal iNKT cells in controlling the pathogenic functions of mucosal T-helper subsets and in maintaining the intestinal immune homeostasis.

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Safety of Recombinant Zoster Vaccine in Patients with Inflammatory Bowel Disease.

In a nationwide cohort of stable IBD patients, administration of RZV was not associated with the risk of IBD flare within 90 days. These findings should motivate further usage of this highly effective vaccine.

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J Hepatol

Endoplasmic reticulum-mitochondria miscommunication is an early and causal trigger of hepatic insulin resistance and steatosis.

The literature suggests that interactions between endoplasmic reticulum (ER) and mitochondria could play a dual role in hepatic insulin resistance and steatosis during chronic obesity. The present study reappraised time-dependent regulation of hepatic ER-mitochondria interactions and calcium exchange in diet-induced obese mice and their causal role in hepatic insulin resistance and steatosis. We show that organelle miscommunication is an early causal trigger of hepatic insulin resistance and steatosis, and can be improved by nutritional strategies.

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Unique molecular characteristics of NAFLD-associated liver cancer accentuate ß-catenin/TNFRSF19-mediated immune evasion.

The unique mutational processes in NAFLD-liver and NAFLD-HCC alludes to a "field effect". Whereby, distinct aberrations and shift in driver events reveal a gain-of-function role of CTNNB1 mutations in immune exclusion via TNFRSF19 inhibition of SASP-like features.

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Neurogastroenterol Motil

A double-blind randomized, multicenter, placebo-controlled study of itopride in functional dyspepsia postprandial distress syndrome.

Using the LPDS score in a pilot controlled trial in FD, itopride shows no therapeutic benefit over placebo after 8 weeks of treatment. In an exploratory post hoc analysis, itopride but not placebo was associated with improvement of symptoms compared to baseline, and this was most prominent in patients with overlapping PDS/EPS. The efficacy of itopride in this subgroup needs to be evaluated in a large study using the same outcome measure. (clinialtrials.org ref. NCT04647955).

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Health-care resource use and costs associated with diabetic and idiopathic gastroparesis: A claims analysis of the first 3 years following the diagnosis of gastroparesis.

The economic burden of gastroparesis remains high several years after diagnosis, emphasizing the need for chronic treatment to effectively manage symptoms and consequently reduce the burden of this disorder.

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Peripheral and central pathophysiological changes in a new rat model of acid reflux combined with mental stress.

Mental stress and acid reflux affect GERD through peripheral and central aspects, which can result in the poor efficacy of acid inhibitors. This may provide a new direction for the treatment of GERD.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Gastroenterology

Disruption of the Mucosal Serotonin Reuptake Transporter (SERT) through Gut Dysbiosis.

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HIF-2 in cancer associated fibroblasts polarizes macrophages and creates an immunosuppressive tumor microenvironment in pancreatic cancer.

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Targeting IRAK4 signaling in PDAC: Turning the 'cold' tumors to 'hot' ones.

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Hepatology

Circulating hepatitis B virus RNA: From biology to clinical applications.

Specifically, we summarized the reported species and existing forms of circulating HBV RNA and discussed their biogenesis and the capacity of de novo infection by RNA virions. Moreover, we described the potential applications of circulating HBV RNA in different clinical scenarios, such as classifying the phases of chronic HBV infection, analyzing sustained on-treatment and off-treatment outcomes of treated patients, as well as predicting hepatocellular carcinoma development. Perspectives on future research of circulating HBV RNA were also proposed in this review.

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The B-side of B cells in NAFLD.

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Inflamm Bowel Dis

Response to the Letter to the Editor: "Re-Revisiting the Association Between Inflammatory Bowel Disease and Parkinson's Disease".

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J Hepatol

Heretical thoughts into Hepatic Encephalopathy.

Many lines of investigation have confirmed that hepatic encephalopathy is irreversible in many patients and suggests the need for further studies focussing on mechanisms of neuronal injury and death to guide future drug development for these patients. The clinical evidence behind using lactulose for al severities of hepatic encephalopathy, which is currently considered the standard of care is poor and placebo-controlled trials for hepatic encephalopathy should be considered ethically sound. This expert opinion identifies current challenges in hepatic encephalopathy and highlights areas which require further debate and investigation in order to help advance the field both scientifically and clinically.

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Neurogastroenterol Motil

Model for multi-disciplinary, multi-institutional virtual learning: The Stanford Esophageal Virtual Collaborative Conference on benign esophageal diseases.

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Role of inflammation in pediatric irritable bowel syndrome.

Likewise, the development of long-standing GI symptoms fulfilling the current criteria for functional GI disorders after infection gastroenteritis and in patients with IBD or celiac disease in remission further supports this hypothesis. Immune activation, its impact on gut sensory-motor function, and potential implications for symptom generation emerged in both children and adults with IBS. Purpose The aim of this review is to summarize the main evidence on the presence of low-grade inflammation and immune activation in children with IBS, its possible role in symptom generation, and its potential implication for new therapeutic strategies.

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Letters&Replies

Letters to the editors and authors’ replies

Clin Gastroenterol Hepatol

Considerations on Self-Expandable Metallic Stents in Treatment of Malignant Biliary Strictures.

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Hepatology

Letter to the Editor: Discussion on application scenario of cell-free DNA fragmentomics in primary liver cancer.

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Letter to the Editor: Hyperosmolarity during hepatic bile formation:Overlooked significance.

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Letter to the editor: the role of acute-on-chronic liver failure in predicting recovery in severe alcoholic hepatitis.

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Non-invasive diagnosis of porto-sinusoidal vascular disease.

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Reply to Non-invasive diagnosis of porto-sinusoidal vascular disease.

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The de-micellization hypothesis of water influx into bile ducts.

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J Hepatol

Cirrhosis. What are all those factor VIII and protein C for?

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EFNA3 is a prognostic biomarker for the overall survival of hepatocellular carcinoma patients.

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Evaluating sarcopenia in cirrhosis patients: the role of muscle function.

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Impact of MELD 30-allocation policy on liver transplant outcomes in Italy: Considerations.

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Reply to: "Gut liver muscle brain axis: a comprehensive viewpoint on prognosis in cirrhosis".

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The CRAFITY score: a promising prognostic predictor for patients with hepatocellular carcinoma treated with tyrosine kinase inhibitor and immunotherapy combinations.

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Others

all remaining publications eg case reports, images of the month, etc…

Am J Gastroenterol

An endoscopy is worth a thousand labs: endoscopic discovery of nonviable intestine in gastrojejunal intussusception.

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Atrioesophageal fistula after ablation of atrial fibrillation.

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Best Practices for the Management of Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation: A Roundtable Discussion and Review.

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Calendar of Courses, Symposiums and Conferences.

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Congenital defect of the gastric musculature without perforation.

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Gastroesophageal Reflux Disease and the Zollinger-Ellison Syndrome.

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Left Out: Disparities in Access to Care Among Foreign-Born Populations and Implications for Hospital-Based Studies.

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Patient-Reported Outcome Assessments in Gastrointestinal Clinical Trials: A Framework for Development and Validation.

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Successful Treatment of Superior Mesenteric Artery Syndrome with Percutaneous Endoscopic Gastrojejunostomy in a Sarcopenic Patient with Cirrhosis.

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The Role of Food in Disorders of Gut-Brain Interaction: Introduction to a Rome Foundation Working Group Series.

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Clin Gastroenterol Hepatol

Comparable survival for hepatitis C-related hepatocellular carcinoma after liver transplantation irrespective of viremic status.

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Statins are under-used in women with NAFLD after cardiovascular events compared to matched controls.

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The Occurrence of Gastritis in Microscopic Colitis and Inflammatory Bowel Disease.

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Endoscopy

Author commentary on Dhairya Mehta et al.

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Author commentary on Hae Won Yoo et al.

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Author commentary on Leonardo Frazzoni et al.

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Author commentary on Linda Y. Zhang et al.

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Author commentary on Mihai Ciocîrlan et al.

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Computer-aided detection is here: will computer-aided quality algorithms soon follow?

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Endoscopic submucosal resection: a new addition to our toolbox?

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Endoscopic tapered sheath-assisted removal of a proximally migrated pancreatic stent.

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Is a location-based resect-and-discard strategy the right approach?

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Novel method to remove deeply migrated pancreatic duct stent.

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Redo-endoscopic ultrasound-guided gastroenterostomy for the management of distal flange misdeployment: trust your orojejunal catheter.

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Reporting endoscopy quality and adverse events: Dutch step forward.

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To-and-fro balloon technique for deployment of a lumen-apposing metal stent in highly solid walled-off necrosis of the pancreas.

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Gastroenterology

AGA Institute Quality Measure Development for the Management of Gastric Intestinal Metaplasia with Helicobacter pylori.

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An Unusual Case of Gallbladder Emergency.

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DETECT: DEvelopment of Technologies for Early HCC deTection.

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Food insecurity complicates diet-based therapy for gastrointestinal diseases.

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Implementation of a Video-Based Remote Germline Testing for Individuals with Pancreatic Ductal Adenocarcinoma.

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One step forward, two steps back? Disproportionate loss of scientific productivity with long-term effects among women and caregivers during the pandemic.

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Probing the microbiome to predict response to biologic therapy in IBD - one step closer to precision medicine?

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Review article, Gastroenterology.

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The Negative Bidirectional Interaction Between Climate Change and the Prevalence and Care of Liver Disease: A Joint BSG, BASL, EASL, and AASLD Commentary.

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THE ROAD TO PROGNOSTICATION? A FIVE-PROTEIN PANEL PREDICTING DISEASE COURSE IN INFLAMMATORY BOWEL DISEASE.

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Trying to Be American: A personal reflection of the pervasiveness of systemic racism and possible steps to mitigate its impact.

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Ulcerating esophageal lesions.

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WOMEN ARE DISADVANTAGED DURING DECEASED DONOR LIVER TRANSPLANT ALLOCATION: STRATEGIES TO OVERCOME INEQUITIES.

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Inflamm Bowel Dis

Natural History of New-onset Inflammatory Bowel Disease Among Patients With Multiple Sclerosis.

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The Sincerest Form of Flattery? Biosimilars in Inflammatory Bowel Disease.

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J Hepatol

A case of HBV-induced liver failure in the REEF-2 Phase 2 trial: Implications for finite treatment strategies in HBV 'cure'.

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The negative bidirectional interaction between climate change and the prevalence and care of liver disease: A joint BSG, BASL, EASL, and AASLD commentary.

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